Reference number
ISO 21766:2021
© ISO 2025
International Standard
ISO 21766:2021
Tobacco and tobacco products — Determination of tobacco-specific nitrosamines in tobacco products — Method using LC-MS/MS
Edition 2
2021-02
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Published (Edition 2, 2021)

ISO 21766:2021

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Format
CHF 98
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Abstract

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

General information

  • Status
     : Published
    Publication date
     : 2021-02
    Stage
    : International Standard published [60.60]
  • Edition
     : 2
    Number of pages
     : 16
  • Technical Committee :
    ISO/TC 126
    ICS :
    65.160 
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